Cystoid Macular Edema in Retinitis Pigmentosa Patients and its Medical Management: A Case Report

Manal Bouggar *

Department of Ophthalmology, Mohammed V Military Hospital, Mohammed V University of Rabat, Morocco.

Houda Brarou

Department of Ophthalmology, Mohammed V Military Hospital, Mohammed V University of Rabat, Morocco.

Zakaria Chaibi

Department of Ophthalmology, Mohammed V Military Hospital, Mohammed V University of Rabat, Morocco.

Yassine Mouzari

Department of Ophthalmology, Mohammed V Military Hospital, Mohammed V University of Rabat, Morocco.

Abdelbare Oubaaz

Department of Ophthalmology, Mohammed V Military Hospital, Mohammed V University of Rabat, Morocco.

*Author to whom correspondence should be addressed.


Abstract

Retinitis Pigmentosa (RP) take in a group of hereditary retinopathies that lead to  progressive vision loss ; RP may be complicated by cystoid macular oedema (CMO). A 40-year-old  female presented with fluctuant blurred vision for 4 years. Best corrected Visual acuity (BCVA) was 20/20 in both eyes. Examination and imaging showed besides  bone spicule pigmentation  a  macular edema . Currently the patient is under medical treatement. Successful management of RP-CMO should allow to improve  quality and quantity of vision in the short term and also slow the progression of  central vision loss on the long term. This report describes a case of using carbonic anhydrase inhibitor CAI per os medication to manage CMO secondary to RP in a long term.

Keywords: Retinitis pigmentosa, macular edema, carbonic anhydrase inhibitor, vision loss


How to Cite

Bouggar , Manal, Houda Brarou, Zakaria Chaibi, Yassine Mouzari, and Abdelbare Oubaaz. 2024. “Cystoid Macular Edema in Retinitis Pigmentosa Patients and Its Medical Management: A Case Report”. Asian Journal of Research and Reports in Ophthalmology 7 (1):85-91. https://journalajrrop.com/index.php/AJRROP/article/view/102.

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References

Chatterjee S, Agrawal D, Agrawal D, Parchand SM, Sahu A. Cataract surgery in retinitis pigmentosa. Indian J Ophthalmol. 2021;69:1753–7.

Liew G, Strong S, Bradley P, Severn P, Moore AT, Webster AR, et al. Prevalence of cystoid macular oedema, epiretinal membrane and cataract in retinitis pigmentosa. Br J Ophthalmol. 2019; 103:1163–6.

Moinuddin O, Sathrasala S, Jayasundera KT, Branham KH, Chang EY, Qian CX, et al. Coats-like exudative vitreoretinopathy in retinitis pigmentosa: ocular manifestations and treatment outcomes. Ophthalmol Retina. 2021;5:86–96

Verbakel SK, van Huet RAC, Boon CJF, den Hollander AI, Collin RWJ, Klaver CCW, Hoyng CB, Roepman R, Klevering BJ. Non-syndromic retinitis pigmentosa. Prog Retin Eye Res. 2018;66: 157-186.

Mnejja M, Hammami B, Bougacha L, Chakroun A, Charfeddine I, Khabir A, Boudaoura T, Ghorbel A. Occult lymph node metastasis in laryngeal squamous cell carcinoma: therapeutic and prognostic impact. European Annals of Otorhinolaryngology, Head and Neck Diseases. 2010;127(5):173-6.

Wolfrum U, Nagel-Wolfrum K. The usher syndrome, a Human Ciliopathy. Klin Monbl Augenheilkd. 2018;235(3):273- 280.

Yang YJ, Peng J, Ying D, Peng QH. A brief review on the pathological role of decreased blood flow affected in retinitis pigmentosa. J Ophthalmol. 2018;2018:32 49064.

Xu H, Chen M, Forrester JV. Para-inflammation in the aging retina. Prog Retin Eye Res. 2009;28(5):348-68.

Shintani K, Shechtman DL, Gurwood AS. Review and update: Current treatment trends for patients with retinitis pigmentosa. Optometry. 2009;80(7):384-401.

Arias JD, Kalaw FGP, Alex V. Investigating the associations of macular edema in retinitis pigmentosa. Sci Rep. 2023;13 :14187.

Strong S, Liew GM. Michaelides Retinitis pigmentosa-associated cystoid macular oedema: pathogenesis and avenues of intervention. Br J Ophthalmol. 2017;101(1): 31–37

Rayapudi S, Schwartz SG, Wang X, Chavis P. Vitamin A and fish oils for retinitis pigmentosa. Cochrane Database Syst Rev. 2013; 2013(12): CD008428.

Schwartz SG, Wang X, Chavis P, Kuriyan AE, Abariga SA. Vitamin A and fish oils for preventing the progression of retinitis pigmentosa. Cochrane Database Syst Rev. 2020 Jun 18;6(6):CD008428.

Fahim A. Retinitis pigmentosa: Recent advances and future directions in diagnosis and management. Curr Opin Pediatr. 2018 ;30:725–33.

Ward J, Meijer P. Visual experiences in the blind induced by an auditory sensory substitution device. Conscious Cogn. 2010;19(1):492-500.

Anil K, Garip G. Coping strategies, vision-related quality of life, and emotional health in managing retinitis pigmentosa: A survey study. BMC Ophthalmol. 2018;18(1):21.

Pacella E, Arrico L, Santamaria V. Dorzolamide chlorhydrate versus acetazolamide in the management of chronic macular edema in patients with retinitis pigmentosa: description of three case reports. Ophthalmol Eye Dis. 2014 ; 6:21–6.

Wang AL, Knight DK, Vu TT, Mehta MC. Retinitis pigmentosa: review of current treatment. Int Ophthalmol Clin. 2019 ; 59:263–80.

Ahn SJ, Kim KE, Woo SJ, et al.. The effect of an intravitreal dexamethasone implant for cystoid macular edema in retinitis pigmentosa: a case report and literature review. Ophthalmic Surg Lasers Imaging Retina. 2014;45:160–4.

Schaal Y, Hondur AM, Tezel TH. Subtenon triamcinolone for cystoid macular edema due to retinitis pigmentosa unresponsive to oral acetazolamide. Can J Ophthalmol. 2016;51:e113–5.