Asian Journal of Research and Reports in Ophthalmology

Sebaceous carcinoma of the Eyelid; A Pseudochalazion Entity : A Case Report and Review of the Literature

Meryam Smiri *

Department of Ophthalmology, Châteaudun Hospital Center, 10 Route de Jallans, 28200, Châteaudun, France.

Mohamed Amine Khoudrani

Department of Ophthalmology, Châteaudun Hospital Center, 10 Route de Jallans, 28200, Châteaudun, France.

Abdeldjalil Mansouri

Department of Ophthalmology, Châteaudun Hospital Center, 10 Route de Jallans, 28200, Châteaudun, France.

Mohamed EL Sanharawi

Department of Ophthalmology, Châteaudun Hospital Center, 10 Route de Jallans, 28200, Châteaudun, France.

*Author to whom correspondence should be addressed.

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Abstract

Palpebral sebaceous carcinoma (PSC) is a rare malignancy originating from sebaceous glands in the eyelid, often mimicking benign inflammatory conditions such as blepharoconjunctivitis or chalazion, leading to diagnostic delays. This article presents a case of a 42-year-old female with a painless upper eyelid lump diagnosed as sebaceous carcinoma. The lesion was successfully treated, resulting in positive functional and aesthetic outcomes. This case underscores the importance of early biopsy and histological examination to distinguish PSC from benign conditions. Current treatment guidelines emphasize surgical excision with margin assessment, and radiotherapy for advanced cases. Establishing follow-up protocols based on melanoma guidelines is recommended due to similar metastatic patterns.

Keywords: Sebaceous carcinoma, eyelid tumor, early diagnosis, chalazion, female, middle aged

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