Asian Journal of Research and Reports in Ophthalmology https://journalajrrop.com/index.php/AJRROP <p style="text-align: justify;"><strong>Asian Journal of Research and Reports in Ophthalmology</strong>&nbsp;aims to publish&nbsp;high-quality&nbsp;papers (<a href="/index.php/AJRROP/general-guideline-for-authors">Click here for Types of paper</a>) in all aspects of&nbsp;‘Ophthalmology’. This journal facilitates the research and wishes to publish papers as long as they are technically correct, scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer-reviewed, open access INTERNATIONAL journal.</p> <p style="text-align: justify;">&nbsp;</p> Asian Journal of Research and Reports in Ophthalmology en-US Asian Journal of Research and Reports in Ophthalmology Nasopharyngeal Cancer with Ophthalmic Revelation: About Three Cases https://journalajrrop.com/index.php/AJRROP/article/view/30112 <p>Nasopharyngeal carcinoma is a major problem in Maghreb. Diagnosis difficult and often at a late stage, this tumor has benefited from the technical progress of radiotherapy. In the stages of complications it can be revealed by ophthalmological manifestations including oculomotorpalsy, papillaryedema or exophthalmia In our series we report three cases of patients with cavumtumors revealed by a papillary edema for the first one, exophthalmia for the second and oculomotorparalysis for the third.</p> Abdi Rhizlane Chariba Siham Asmae Maadan Rachid Sekhsoukh ##submission.copyrightStatement## 2020-05-24 2020-05-24 7 12 A Rare Finding of an Early Anterior Polar Cataract after Burn Injury https://journalajrrop.com/index.php/AJRROP/article/view/30114 <p><span style="text-decoration: underline;"></span><span style="text-decoration: underline;"></span><span style="text-decoration: underline;"></span></p> <p>Ocular chemical injuries are true ophthalmic emergencies that require immediate and intensive intervention to minimize severe complications and profound visual loss [1]. They mostly affect young active men; causes include domestic accidents, workplace-related injuries and assaults [2]. Acid or base chemical burns can lead to serious lesions, of which corneal ulcer and limbal or conjunctival ischemia are the most common. However, several other complications have been described in the literature such as chronic dry eye, symblepharons and rarely cataracts. &nbsp;Our work reports a case of an early onset cataract after a chemical burn, this is an unusual complication especially by its type and its time of onset.</p> Fatine El Alami Rajaa Boubsir Selma Chiguer Adil Mchachi Laila Benhmidoune Abderrahim Chakib Rayad Rachid Mohamed Elbelhadji ##submission.copyrightStatement## 2020-07-01 2020-07-01 17 20 Dry Eye Syndrome Secondary to Kohl (Eyepencil) https://journalajrrop.com/index.php/AJRROP/article/view/30113 <p>Dry eyes are becoming a part of people’s lives more and more frequently.&nbsp;Usage of eye cosmetics is known to cause disturbances in the stability of tear film and cause dry eye symptoms we conducted a prospective study on a sample of 100 women whose age ranged from 18 to 35 years in university hospital center MOHAMMED VI OUJDA&nbsp; MOROCCO on a period of 6 months from January 2019 to JUNE 2019. The aim of thisstudyis to determine the effect of applying Kajal (an eyecosmetic) over the eyelids on tear film stability and quantity.</p> Abdi Rhizlane Chariba Siham Asmae Maadan Rachid Sekhsoukh ##submission.copyrightStatement## 2020-06-22 2020-06-22 13 16 Genetic Diagnosis of Glaucoma https://journalajrrop.com/index.php/AJRROP/article/view/30115 <p><strong>Purpose</strong><strong>:</strong> Glaucoma, the most prevalent cause of irreversible blindness across the world, is progressive optic nerve degeneration and affection (neuropathy) caused by a mixture of both genetic and environmental factors [1]. The extracellular matrix (ECM) structure of the trabecular Meshwork TM has a major role in intraocular pressure IOP control. <sup>&nbsp;</sup>Transforming growth factor beta (TGF-β) is a growth factor that plays major roles in cellular functions, including encouraging extracellular matrix synthesis and vascular angiogenesis. TGFβ2 treatment of TM cells alters ECM components [8] and induces ECM bonds.</p> <p><strong>Aim of the Study</strong><strong>: </strong>To study the relationship between family history and glaucoma according to genotype and genetic polymorphism.</p> <p><strong>Methods</strong><strong>:</strong> Blood collection and DNA extraction Genotyping: TGFB2 Rs99196 genotyping was done using TaqMan SNP genotyping Assay (ID C___8853564_10). StepOne real time PCR system (Applied Biosystem, Ca, USA) was used for amplifiction.</p> <p><strong>Statistical Analysis</strong><strong>:</strong> The sample size of the study group was calculated using a program at (www.openepi.com/SampleSize/ SSCC.htm).</p> <p><strong>Results</strong><strong>:</strong> Important genotype differences frequencies were detected between the positive family history and negative family history groups for the codominant, dominant, recessive and overdominant inheritance models.</p> <p><strong>Conclusion</strong><strong>:</strong> This study recommends that other polymorphisms of genes associated with glaucoma and the analysis of these gene products and their relationship with disease risk factors should be more studied.</p> Hany Mahmoud Marwa S. Hashim ##submission.copyrightStatement## 2020-07-06 2020-07-06 21 25 Ocular Chemical Injury: Role of Amphoteric Agents as an Alternative Irrigating Solution https://journalajrrop.com/index.php/AJRROP/article/view/30111 <p>Chemical eye injury is a true ocular emergency that requires a prompt decision and immediate management by using an irrigating solution to the eye. The development of a new solution, such as amphoteric agents are now used in comparison to conventional agents. This type of solution reacts rapidly with both acids and alkalis. It also has hypertonic properties, thus resulting in milder corneal edema and mobilizes the diffusion of corrosive agents out of the eye structure. Several studies indicated that the amphoteric solution had significantly better clinical and ocular outcomes compared to other irrigation fluids. Irrigation using amphoteric agents found to shorten the time of corneal reepithelization in Grade I-II chemical eye injury. It also resulted in a better outcome for visual acuity, pain intensity, severity of the injury, and less further complications. In conclusion, prompt eye irrigation using the amphoteric solution shown as a better alternative in chemical ocular injury. Thus, its usage may be suggested for future management for chemical eye injury.</p> Krisnhaliani Wetarini Fransiska Lavinia Gracella ##submission.copyrightStatement## 2020-05-19 2020-05-19 1 6